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Hongzhuan Chen Selected Research

Reactive Oxygen Species (Oxygen Radicals)

1/2019CuS Nanoparticles as a Photodynamic Nanoswitch for Abrogating Bypass Signaling To Overcome Gefitinib Resistance.
1/2017Design, synthesis, biological evaluation, and molecular modeling studies of chalcone-rivastigmine hybrids as cholinesterase inhibitors.
11/2012N-acetylcysteine protects against hypoxia mimetic-induced autophagy by targeting the HIF-1α pathway in retinal ganglion cells.

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Hongzhuan Chen Research Topics

Disease

26Alzheimer Disease (Alzheimer's Disease)
01/2022 - 06/2009
23Neoplasms (Cancer)
01/2022 - 11/2011
8Memory Disorders (Memory Loss)
01/2021 - 03/2014
7Glioma (Gliomas)
03/2020 - 11/2011
7Gliosis
12/2019 - 07/2014
6Neuroinflammatory Diseases
01/2021 - 01/2008
5Lung Neoplasms (Lung Cancer)
01/2020 - 01/2015
4Hypoxia (Hypoxemia)
11/2021 - 06/2009
4Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2019 - 01/2015
3Neoplasm Metastasis (Metastasis)
01/2018 - 12/2013
3Glaucoma
05/2011 - 06/2009
2Neurodegenerative Diseases (Neurodegenerative Disease)
05/2022 - 06/2009
2Inflammation (Inflammations)
01/2022 - 01/2018
2Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2021 - 06/2015
2COVID-19
10/2020 - 07/2020
2Ischemic Stroke
12/2019 - 01/2017
2Brain Diseases (Brain Disorder)
01/2019 - 03/2014
2Glioblastoma (Glioblastoma Multiforme)
08/2015 - 07/2013
2Neuroblastoma
06/2009 - 01/2008
1Parkinson Disease (Parkinson's Disease)
05/2022
1Colorectal Neoplasms (Colorectal Cancer)
01/2022
1Stomach Neoplasms (Stomach Cancer)
01/2022
1Hepatocellular Carcinoma (Hepatoma)
11/2021
1Virus Diseases (Viral Diseases)
10/2021
1Turcot syndrome
01/2021
1Leukemia
01/2021
1Melanoma (Melanoma, Malignant)
01/2021
1Triple Negative Breast Neoplasms
01/2021
1Multiple Myeloma
01/2020
1Traumatic Brain Injuries (Traumatic Brain Injury)
01/2020

Drug/Important Bio-Agent (IBA)

14Pharmaceutical PreparationsIBA
01/2020 - 04/2010
13Peptides (Polypeptides)IBA
01/2022 - 06/2009
8Cholinergic Agents (Cholinergics)IBA
11/2019 - 01/2008
7Paclitaxel (Taxol)FDA LinkGeneric
08/2015 - 11/2011
6Amyloid (Amyloid Fibrils)IBA
01/2022 - 09/2014
6AcetylcholinesteraseIBA
01/2019 - 02/2012
6Amyloid beta-PeptidesIBA
11/2016 - 06/2009
6LigandsIBA
08/2015 - 01/2008
5Potassium Channels (Potassium Channel)IBA
10/2017 - 07/2014
5monomethoxypolyethyleneglycol- polylactide block copolymerIBA
09/2014 - 06/2013
4Proteins (Proteins, Gene)FDA Link
05/2022 - 06/2009
4Lipoproteins (Lipoprotein)IBA
03/2020 - 03/2014
3Oxygen (Dioxygen)IBA
11/2021 - 01/2017
3Glucose (Dextrose)FDA LinkGeneric
11/2021 - 01/2017
3Acetylcholine (Acetylcholine Chloride)FDA Link
12/2020 - 10/2015
3Neuroprotective AgentsIBA
11/2020 - 11/2012
3Reactive Oxygen Species (Oxygen Radicals)IBA
01/2019 - 11/2012
3Intermediate-Conductance Calcium-Activated Potassium ChannelsIBA
10/2016 - 07/2014
3Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA
01/2015 - 06/2009
3cobaltous chloride (cobalt(II)chloride)IBA
11/2012 - 06/2009
22-mercaptopurineIBA
01/2021 - 06/2015
2Glutamic Acid (Glutamate)FDA Link
11/2020 - 11/2015
2MicroRNAs (MicroRNA)IBA
03/2020 - 01/2018
2CalciumIBA
12/2019 - 01/2018
2Insulin (Novolin)FDA Link
12/2019 - 01/2019
2Gefitinib (Iressa)FDA Link
01/2019 - 01/2018
2ErbB Receptors (EGF Receptor)IBA
01/2018 - 11/2017
2Tyrosine Kinase InhibitorsIBA
01/2018 - 11/2017
2Glial Fibrillary Acidic ProteinIBA
01/2017 - 07/2014
2SolutionsIBA
11/2015 - 07/2013
2Muscarinic M2 ReceptorIBA
10/2015 - 01/2015
2Transferrin (beta 2 Transferrin)IBA
08/2015 - 06/2013
2Biological ProductsIBA
08/2015 - 11/2008
2NeurotoxinsIBA
04/2015 - 01/2008
2polyethylene glycol-poly(lactide-co-glycolide)IBA
05/2014 - 11/2011
2Matrix Metalloproteinases (MMPs)IBA
07/2013 - 03/2013
2Pilocarpine (Ocusert)FDA LinkGeneric
04/2010 - 06/2009
2PMS 777IBA
06/2009 - 01/2008
1SynucleinsIBA
05/2022
1CationsIBA
05/2022
1PolymersIBA
01/2022
1Circular RNAIBA
01/2022
1CytokinesIBA
01/2022
1XanthonesIBA
01/2022
1bruceine DIBA
11/2021
1CateninsIBA
11/2021
1QuassinsIBA
11/2021
1SARS-CoV-2 spike proteinIBA
10/2021
1EnzymesIBA
10/2021
1AntibodiesIBA
01/2021
1Capsaicin (Zostrix)FDA Link
01/2021
1Peptide Hydrolases (Proteases)FDA Link
01/2021
1Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
01/2021
1Wasp Venoms (Venom, Wasp)IBA
01/2021
1Antiviral Agents (Antivirals)IBA
07/2020
1jinhua qinggan granulesIBA
07/2020
1XuebijingIBA
07/2020
1Nonprescription Drugs (Patent Medicines)IBA
07/2020
1Therapeutic UsesIBA
03/2020
1CXCR4 Receptors (CXCR4 Receptor)IBA
03/2020
1Cyclosporine (Ciclosporin)FDA LinkGeneric
01/2020
1Dexamethasone (Maxidex)FDA LinkGeneric
01/2020
1Lenalidomide (CC 5013)FDA Link
01/2020
1CopperIBA
01/2020

Therapy/Procedure

16Therapeutics
01/2020 - 05/2011
5Immunotherapy
01/2022 - 01/2018
3Drug Therapy (Chemotherapy)
01/2022 - 09/2014
2Intranasal Administration
11/2015 - 02/2012
2Intravenous Administration
09/2014 - 05/2014
1Chinese Traditional Medicine (Traditional Chinese Medicine)
10/2020